The impedance of a series circuit with a capacitor (100 ohms), inductor (300 ohms), and resistor (400 ohms) can be calculated using vector addition of voltages. The voltage across the capacitor leads the current by 90 degrees, while the voltage across the inductor lags by 90 degrees, and the voltage across the resistor corresponds directly to the current. The total voltage, V_s, is the vector sum of these voltages, expressed as V_s = √((V_c - V_L)² + V_r²). This leads to the formula for impedance, Z = √((X_c - X_L)² + r²), resulting in an impedance of √(200kΩ). The discussion emphasizes the importance of understanding phase relationships in AC circuits for accurate impedance calculations.