Synthesizing alkyne from alcohol

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To transform an alcohol attached to a carbon chain into an alkyne, the process typically involves several key steps. Initially, the alcohol can be dehydrated using concentrated sulfuric acid and heat to form an alkene, although the suitability of this method depends on the sensitivity of other functional groups present in the molecule. Following alkene formation, elemental bromine (Br2) can be added to create a dibromo compound. The final step involves a double dehydrohalogenation using an eliminating agent such as NaOH in glycerol or KOH in ethanol, which leads to the formation of a triple bond, resulting in the desired alkyne. Additional details about the specific carbon chain structure may be needed for more tailored advice.
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If I have a end alcohol attached to a carbon chain, what would be a reaction or synthetic pathway that can be done to transform the alcohol to an alkyne? Thanks for your input.
 
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hi,
well it generally depends on the chain. If there are some super sensitive functional groups you don't have much options, you have to do some protections and such stuff. As an example , you can use conc. sulfuric acid and heat to make an alkene (depends on the carbon chain if you can use such a strong dehydrating agent) than you can add elemental bromine, Br2 to the double bond to make a dibromo compound and then you use an eliminating agent such as NaOH in glycerol (or a more standard KOH/ethanol) to do a double dehydrohalogenation to form a tripple bond ... if this doesn't help I'm very sorry but you'll have to provide more info on the substance you mean to use.
 
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