Why is the dehydration synthesis also called a condensation reaction?

AI Thread Summary
Condensation refers to the process of changing from a gas to a liquid, but in biochemical contexts, it also describes reactions where small molecules combine, releasing water. The formation of peptide bonds between amino acids is a specific type of condensation reaction, as it results in the release of water (H2O) when the amine group donates a hydrogen atom and the carboxylic acid group donates a hydroxyl group. This reaction highlights the dual use of the term "condensation," which in Latin means "to thicken," applicable to both physical and chemical processes. The discussion clarifies that nucleotides and amino acids are not gases during these reactions; rather, the term is used to describe the overall process of bond formation and water release.
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Doesn't condensation imply a change from a gas to a liquid?

Were the nucleotides gases when the phosphodiester bond formed?
Were the amino acids gases when the peptide bond formed?
 
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It is just the same name used for two different processes. In latin condensatio means to thicken, it happens that it fits both cases.

Borek
 
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Thanks.
 
The formation of the peptide bond is called a condensation reaction since one H2O is produced when two amino acids bond.
The NH3 amine group donates one H and the COOH acid group donates an
OH . The peptide bond then is between N-C
 
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