How Do You Calculate Shear Stress in a Coronary Artery?

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SUMMARY

The discussion focuses on calculating shear stress in a coronary artery with a diameter of 2.5 mm and a length of 3 cm, where blood flows at an average velocity of 1.5 cm/s. The shear stress (τ) is derived using the formula τ = μ ∂u/∂y, where viscosity (μ) is given as 3 cP. Participants explore the velocity gradient at the wall and the parabolic flow profile, emphasizing the relationship between maximum velocity and average velocity in fully developed flow conditions.

PREREQUISITES
  • Understanding of fluid dynamics principles, particularly shear stress calculations.
  • Familiarity with the concepts of viscosity and flow profiles in blood vessels.
  • Knowledge of calculus, specifically derivatives and their application in fluid mechanics.
  • Basic understanding of coronary artery anatomy and blood flow characteristics.
NEXT STEPS
  • Study the derivation of the parabolic velocity profile in laminar flow through cylindrical tubes.
  • Learn about the relationship between maximum velocity and average velocity in fully developed laminar flow.
  • Explore the application of the Navier-Stokes equations in biological fluid dynamics.
  • Investigate the effects of varying viscosity on shear stress in different blood flow scenarios.
USEFUL FOR

Medical researchers, biomedical engineers, and students studying cardiovascular physiology who are interested in fluid dynamics and shear stress calculations in coronary arteries.

Gwozdzilla
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Homework Statement


Blood supply to the heart occurs through coronary arteries. Consider one of the arteries to be 2.5 mm in diameter and 3 cm in length. The average velocity of blood flow through that artery is 1.5 cm/s. Assuming the density of blood to be 1.056 g/cc and viscosity to be 3 cP (3x10-3 Ns/m2). Estimate the shear stress at the wall.

Homework Equations


τ = μ ∂u/∂y = shear stress = (viscosity) (d(velocity))/(dy)

The Attempt at a Solution


τ = (3cP)(1.5cm/s)

I'm not sure how to estimate ∂u/∂y. Is it equal to the average velocity? I think that when the blood reaches fully developed flow, it's shaped like a parabola and it's velocity is constant at a given y, but I'm not sure how to apply this information to understand the formula.
 
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Indeed, the flow profile is a quadratic function of radius. See http://hyperphysics.phy-astr.gsu.edu/hbase/pfric.html#vel.
Using that formula and knowing the average flow, you should be able to write out exactly how the flow rate depends on radius for this example. From that you can find the velocity gradient at the wall.
 
From Haruspex's link, how is the maximum velocity at the center of the artery related to the average velocity in the problem statement? Since the shape of the velocity profile is parabolic in r and the velocity is zero at the wall of the capillary, what is the equation for v(r) in terms of r, the average velocity, and the wall radius? What is the derivative of v with respect to r at the wall?

Chet
 

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