A nuclear reactor producing 30,000 kW of energy releases approximately 200 MeV per fission of U-235. To calculate the number of U-235 atoms undergoing fission per second, one must first convert the total energy output into joules and then divide by the energy released per fission event. The discussion emphasizes the importance of considering the efficiency of the power plant when discussing net electrical output versus thermal power. Additionally, it notes that a typical nuclear power plant aims to produce a limited amount of radioactive waste relative to its output. The calculations for U-235 usage over 1,000 hours of operation can be derived from these principles.