Predicting charge of organic compound at certain pH

AI Thread Summary
The discussion centers on the role of pKa and pKb in predicting the charge of organic compounds at specific pH levels. It is established that pKa and pKb are crucial for understanding acid-base reactions, particularly protonation, and are generally sufficient for predicting charges. The conversation indicates a consensus on the importance of these properties, with no counterexamples presented to challenge their relevance. The participants express satisfaction with this understanding, confirming that pKa and pKb are key indicators in this context.
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Which property of compounds, organic ones in particular, can help us predict their charge(s) at a specific pH? Is pKa/pKb the only one? I would like some confirmation on this. Thank you very much!
 
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pKa and pKb help predict charges related to the acid/base (mostly protonoation) reactions. As these dominate, pKa/pKb is usually enough.

Actually I can't think of a counterexample ATM. Which probably means I will feel ashamed later today.
 
Borek said:
pKa and pKb help predict charges related to the acid/base (mostly protonoation) reactions. As these dominate, pKa/pKb is usually enough.

Actually I can't think of a counterexample ATM. Which probably means I will feel ashamed later today.
This information is enough. Thank you very much!
 
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