SIS epidemics transition matrix

In summary, a health company is interested in studying the spread of a disease in a population of 50 people. The disease follows SIS dynamics, with a 0.1 probability of an infected individual increasing the number of infected individuals, a 0.05 probability of a decrease, and a 0.85 probability of no change. The transition matrix for this process would be a 51x51 matrix, and the state space would consist of all possible numbers of infected individuals from 0 to 50.
  • #1
Mark53
93
0

Homework Statement


[/B]
The population is 50

The diseases is known to follow SIS dynamics with the following probabilities

The number of infected individuals increases with probability 0.1

and it decreases with probability 0.05

the probability that nothing happens is 0.85

a) what is the transition matrix P?

The Attempt at a Solution


[/B]
Would this mean my transition matrix would look like this
\begin{bmatrix}0.85 & 0.1 & 0.05 \\ 0.05 & 0.85 & 0.1\\ 0.1 & 0.05 & 0.0.85 \end{bmatrix}

Does this mean my sate space would be (1 to 50)
 
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  • #2
Mark53 said:

Homework Statement


[/B]
The population is 50

The diseases is known to follow SIS dynamics with the following probabilities

The number of infected individuals increases with probability 0.1

and it decreases with probability 0.05

the probability that nothing happens is 0.85

a) what is the transition matrix P?

The Attempt at a Solution


[/B]
Would this mean my transition matrix would look like this
\begin{bmatrix}0.85 & 0.1 & 0.05 \\ 0.05 & 0.85 & 0.1\\ 0.1 & 0.05 & 0.0.85 \end{bmatrix}

Does this mean my sate space would be (1 to 50)

The question makes very little sense as written. Do you mean that each non-infected individual becomes infected with probability 0.1 (independent of others), that each infected individual becomes non-infected with probability .05 (independent of others), and that each individual's status remains unchanged with probability 0.85? If so, you need to have state-space 0,1,2,...,50 (the number of infected individuals at any time). Then, if the state at time ##t## is ##X(t) = k## for some ##k \in \{0,1,\ldots, 50\},## how would you compute the probabilities that ##j## individuals are infected at time ##t+1##? Your transition matrix will be a ##51 \times 51## matrix whose entries are those probabilities.
 
  • #3
My guess is that the question is this is a birth-death process, where you get one more sick person with probability ##p##, one less sick person with probability ##q##, and stay in same state with probability ##1 - p - q##. The question... could definitely be tightened up in its wording though.

The two exceptions for these transition probabilities are corner states --- i.e. when all 50 people are sick OR when 1 (or 0?) people are sick -- then you need to make appropriate tweaks to ##p## and ##q## respectively. (If it's a zoonotic or infected foreign persons come 'pop in' or what have you, you could still have 0 people sick in your population area yet have reoccurrences of the disease.) So the state space is ##\{0, 1, 2, ..., 49, 50\}## or ##\{1, 2, ..., 49, 50\}## depending on whether 0 is allowed.
 
  • #4
StoneTemplePython said:
My guess is that the question is this is a birth-death process, where you get one more sick person with probability ##p##, one less sick person with probability ##q##, and stay in same state with probability ##1 - p - q##. The question... could definitely be tightened up in its wording though.

The two exceptions for these transition probabilities are corner states --- i.e. when all 50 people are sick OR when 1 (or 0?) people are sick -- then you need to make appropriate tweaks to ##p## and ##q## respectively. (If it's a zoonotic or infected foreign persons come 'pop in' or what have you, you could still have 0 people sick in your population area yet have reoccurrences of the disease.) So the state space is ##\{0, 1, 2, ..., 49, 50\}## or ##\{1, 2, ..., 49, 50\}## depending on whether 0 is allowed.

Yes: that makes a lot of sense, and gives a much more tractable model.
 
  • #5
StoneTemplePython said:
My guess is that the question is this is a birth-death process, where you get one more sick person with probability ##p##, one less sick person with probability ##q##, and stay in same state with probability ##1 - p - q##. The question... could definitely be tightened up in its wording though.

The two exceptions for these transition probabilities are corner states --- i.e. when all 50 people are sick OR when 1 (or 0?) people are sick -- then you need to make appropriate tweaks to ##p## and ##q## respectively. (If it's a zoonotic or infected foreign persons come 'pop in' or what have you, you could still have 0 people sick in your population area yet have reoccurrences of the disease.) So the state space is ##\{0, 1, 2, ..., 49, 50\}## or ##\{1, 2, ..., 49, 50\}## depending on whether 0 is allowed.
when multiplying the state space by the transition matrix

How would I know if the individual is infected or not?
 
  • #6
Mark53 said:
when multiplying the state space by the transition matrix

How would I know if the individual is infected or not?

I'm not sure I follow. The states refer to total number of infected individuals -- knowing whether "the individual" is infected is unrelated / doesn't make sense to ask with respect to the model I'm suggesting. What course is this for? Are you familiar with a birth-death process? You should be able to work out the steady state by hand...

Alternatively, type in the exact problem as I'm just guessing this is a birth death process. The question posed in your original post... leaves a lot to be desired in terms of clarity.
 
  • #7
StoneTemplePython said:
I'm not sure I follow. The states refer to total number of infected individuals -- knowing whether "the individual" is infected is unrelated / doesn't make sense to ask with respect to the model I'm suggesting. What course is this for? Are you familiar with a birth-death process? You should be able to work out the steady state by hand...

Alternatively, type in the exact problem as I'm just guessing this is a birth death process. The question posed in your original post... leaves a lot to be desired in terms of clarity.

A Health company would like to see how a disease will spread if one infected individual was to arrive in a country with a population of 50 people.

The diseases is known to follow SIS (susceptible-infected-susceptible) dynamics with the following probabilities

The number of infected individuals increases with probability 0.1

and it decreases with probability 0.05

the probability that nothing happens is 0.85

Would the state space still be 1 to 50 for this? and a 50x50 transition matrix?
 
  • #8
Mark53 said:
A Health company would like to see how a disease will spread if one infected individual was to arrive in a country with a population of 50 people.

The diseases is known to follow SIS (susceptible-infected-susceptible) dynamics with the following probabilities

The number of infected individuals increases with probability 0.1

and it decreases with probability 0.05

the probability that nothing happens is 0.85

Would the state space still be 1 to 50 for this? and a 50x50 transition matrix?

I still don't know what course this is for / whether you are familiar with a birth-death process. I have never heard of an SIS dynamic before -- SIS is not a standard term in probability or linear algebra. Providing definitions to the message board for non-standard terms is... generally beneficial.

With respect to your question, which I bolded, what I said before still stands

StoneTemplePython said:
M So the state space is ##\{0, 1, 2, ..., 49, 50\}## or ##\{1, 2, ..., 49, 50\}## depending on whether 0 is allowed.

so its either a 50 x 50 transition matrix or 51 x 51, depending on whether zero is legal.
 
  • #9
StoneTemplePython said:
I still don't know what course this is for / whether you are familiar with a birth-death process. I have never heard of an SIS dynamic before -- SIS is not a standard term in probability or linear algebra. Providing definitions to the message board for non-standard terms is... generally beneficial.

With respect to your question, which I bolded, what I said before still stands
so its either a 50 x 50 transition matrix or 51 x 51, depending on whether zero is legal.

its a probability course and I have heard of the birth-death process

SIS means going from susceptible to the disease to being infected to returning to being susceptible

given that 1 individual is already infected the state space must be 1 to 50
 
  • #10
It really depends on what you're trying to model and why. Birth-death could makes sense.

You could also model it on an individual person level (susceptible, infected, susceptible), figure out on average the percent of time a person is sick (there will be one eigenvalue = 1, and all others have magnitude less than that in your original 3x3 transition matrix), and from there use linearity of expectations to figure out on average the number of people who are sick, and so on.

The question really could use a re-write for clarity on what exactly it is getting at and perhaps why. (Though that is out of your hands, I know.)
 
  • #11
Mark53 said:
its a probability course and I have heard of the birth-death process

SIS means going from susceptible to the disease to being infected to returning to being susceptible

given that 1 individual is already infected the state space must be 1 to 50

Not necessarily: if eventually the disease can be eradicated, then the state space is {0,1,...,50}. Just because you start at state 1 does not mean that you cannot achieve state 0 in the future.
 

1. What is a SIS epidemics transition matrix?

A SIS epidemics transition matrix is a mathematical model used to study the spread of a disease within a population. It tracks the movement of individuals between two states - susceptible (S) and infected (I) - and the rate at which they transition from one state to another.

2. How is the transition matrix used in studying epidemics?

The transition matrix is used to calculate the basic reproduction number (R0) of a disease, which is the average number of secondary infections caused by a single infected individual in a susceptible population. It also helps to predict the spread and control of the disease.

3. What factors are included in the SIS epidemics transition matrix?

The transition rates in the matrix are influenced by factors such as the infectiousness of the disease, the duration of infection, and the contact rates between susceptible and infected individuals in the population.

4. How is the transition matrix updated during an epidemic?

As the epidemic progresses and individuals recover or become re-infected, the transition matrix is updated to reflect these changes. This allows for a more accurate prediction of the spread of the disease and the effectiveness of control measures.

5. Can the SIS epidemics transition matrix be used for all diseases?

No, the SIS epidemics transition matrix is specifically designed for diseases that do not confer immunity after recovery. It is not suitable for diseases such as measles, where individuals become immune after recovering from the infection.

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