Total peripheral resistance and the diastolic pressure

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Total peripheral resistance (TPR) affects diastolic pressure more significantly than systolic pressure due to the nature of blood flow and vascular dynamics. During diastole, the heart is relaxed, and the arteries experience sustained pressure from the blood volume that remains in the system. Increased TPR leads to higher resistance against blood flow, which elevates diastolic pressure as the heart fills. In contrast, during systole, the heart contracts and ejects blood, which is less influenced by TPR since the pressure is primarily driven by the force of contraction. Understanding this physiological relationship clarifies why TPR has a more pronounced effect on diastolic pressure. The relevant equation, ABP = SV * HR * TPR, illustrates the relationship between arterial blood pressure, stroke volume, heart rate, and TPR, but the focus remains on the physiological implications of resistance in the vascular system.
Asmaa Mohammad
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Hello,

I came across this line in my textbook:
"Total peripheral resistance (TPR) increases diastolic pressure more than systolic pressure."

I don't understand how the peripheral resistance would increase the diastolic pressure more than the systolic pressure?

Could some one explain that for me?

Thanks!
 
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Asmaa Mohammad said:
Hello,

I came across this line in my textbook:
"Total peripheral resistance (TPR) increases diastolic pressure more than systolic pressure."

I don't understand how the peripheral resistance would increase the diastolic pressure more than the systolic pressure?

Could some one explain that for me?

Thanks!
Can you post the Relevant Equations? There are several equations that apply... :smile:
 
berkeman said:
Can you post the Relevant Equations? There are several equations that apply... :smile:
The equation in the book is:
ABP = SV * HR * TPR
(Arterial blood pressure = stroke volume * Heart rate * total peripheral resistance)

But I want to understand the physiological part not the marhematical one.
 

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