What is acet in organic chemistry?

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SUMMARY

The discussion focuses on the acetyl group (CH3CO) and its significance in organic chemistry, particularly in relation to compounds like acetophenone and acetic acid. The acetyl radical is not part of standard IUPAC nomenclature but is widely recognized in common naming conventions. Acetyl groups play a crucial role in biological processes, including the conversion of pyruvate to acetyl-CoA, which is essential for fatty acid biosynthesis and protein acetylation. This acetylation process is vital for regulating gene expression through modifications of histone proteins.

PREREQUISITES
  • Understanding of organic chemistry nomenclature
  • Knowledge of metabolic pathways, specifically glycolysis
  • Familiarity with coenzyme A (CoA) and its functions
  • Basic concepts of protein modification and gene expression
NEXT STEPS
  • Research the role of acetyl-CoA in fatty acid biosynthesis
  • Study the process of protein acetylation and its impact on gene regulation
  • Explore the differences between IUPAC and common naming conventions in organic chemistry
  • Learn about the biochemical pathways involving pyruvate and acetyl groups
USEFUL FOR

Students and professionals in organic chemistry, biochemistry researchers, and anyone interested in the metabolic roles of acetyl groups in biological systems.

Logic hunter
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What does it mean and why do acetophenone and acetic acid have it in their name ?
 
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Think about it for just a moment.
 
Bystander said:
Think about it for just a moment.
CH3CO, as I guessed but how do you use it in nomenclature in a standard way.
 
Yes, a CH3-(C=O)-R group is commonly referred to as an acetyl radical. Note that this is not standard IUPAC nomenclature, so names using the root acetyl are mostly common names for compounds and there are no formal rules for its use in the names of compounds.

The acetyl group is particularly important in various aspects of biology. Acetyl groups can be generated from pyruvate, the end product of glycolysis. Decarboxylation of pyruvate transfers an acetyl radical from pyruvate to a vitamin called coenzyme A (CoA), and the acetyl group from the resulting acetyl-CoA molecule can then be transferred to other substrates or used as a building block for other metabolic processes (such as fatty acid biosynthesis). One important acetylation reaction is the transfer of the acetyl group from coenzyme A to lysine residues in proteins. Acetylation of the histone proteins that help wrap and package DNA is thought to be very important for regulating gene expression and other biological processes involving DNA.
 
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