To calculate the resultant force on charge q3 in an electric field created by charges q1 and q2, first apply Coulomb's Law to determine the forces exerted by q1 and q2 on q3. The formula for the force between two charged particles is F = k * |q1 * q2| / r^2, where k is Coulomb's constant, and r is the distance between the charges. After calculating the individual forces, vector addition is necessary to find the resultant force, taking into account the direction of each force. It is crucial to remember that forces are vectors, so both magnitude and direction must be considered. Understanding these principles will enable the accurate calculation of the resultant force on q3.