The working fluid temperatures in high temperature reactors are higher than those in conventional LWRs, and the materials are necessarily different.
Let's consider LWRs.
PWRs (pressurized water reactors) operate with a primary circuit temperature of about 285-293°C inlet and about 325-330°C outlet at a nominal pressure of ~2270 psia. The fuel is subject to a number of engineering constraints under normal and off-normal conditions (NUREG-0800, Chapter 4.2). Basically the fuel is not allowed to melt (no centerline melting), must have less than 1% strain, and must not allow cladding lift-off in the event of design basis transients.
BWRs operate with the coolant at saturation conditions with a nominal core pressure of about 1045-1055 psia.
In LWRs the cladding material is an alloy of Zr and usually Zr-Sn or Zr-Nb with other alloying elements, e.g. Fe, Cr, Ni and others in lesser quantities. The fuel is UO
2 or (U, Pu)O
2, with additions of gadolinia, erbia or ZrB
2 for reactivity control.
High temperature plants can use He (gas), Na or Pb (Pb-Bi) (liquid metal), molten salt or H
2O. With respect to H
2O, there is consideration of a supercritical water reactor which would have an operating conditions exceeding (374°C, 22 MPa, or 705°F, 3208 psia). Fuel materials could be cermet or metal fuel or UN, UC or (U,Pu)N or (U,Pu)C or possibly silicide.
See the concept here -
http://nuclear.inl.gov/gen4/index.shtml
The operating environments of the Gen IV concepts are very challenging for the materials and engineering.
The idea is however to increase the temperature in order to increase the efficiency. In addition to producing electrical power, heat would also be used for chemical processes, e.g. hydrodgen production using the S-I process.