Predicting charge of organic compound at certain pH

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SUMMARY

The discussion centers on predicting the charge of organic compounds at specific pH levels, emphasizing the significance of pKa and pKb values. Participants confirm that pKa and pKb are the primary tools for predicting charges associated with acid/base protonation reactions. No counterexamples to this assertion were provided, reinforcing the consensus that pKa and pKb are sufficient for this purpose.

PREREQUISITES
  • Understanding of pKa and pKb values
  • Knowledge of acid/base chemistry
  • Familiarity with protonation reactions
  • Basic concepts of organic chemistry
NEXT STEPS
  • Research the relationship between pH and pKa in organic compounds
  • Explore the concept of protonation and its effects on molecular charge
  • Learn about the role of pKb in predicting base behavior
  • Investigate examples of organic compounds with varying pKa values
USEFUL FOR

Chemistry students, organic chemists, and researchers focusing on acid/base reactions and charge prediction in organic compounds.

Baho Ilok
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Which property of compounds, organic ones in particular, can help us predict their charge(s) at a specific pH? Is pKa/pKb the only one? I would like some confirmation on this. Thank you very much!
 
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pKa and pKb help predict charges related to the acid/base (mostly protonoation) reactions. As these dominate, pKa/pKb is usually enough.

Actually I can't think of a counterexample ATM. Which probably means I will feel ashamed later today.
 
Borek said:
pKa and pKb help predict charges related to the acid/base (mostly protonoation) reactions. As these dominate, pKa/pKb is usually enough.

Actually I can't think of a counterexample ATM. Which probably means I will feel ashamed later today.
This information is enough. Thank you very much!
 

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